Tuesday, February 8, 2011

Anti-Aging Research: More Evidence of the Skin Rejuvenating Effects of LED Therapy

[Thanks to reader Pat for alerting me to this information which was published in the December 2009 issue of the Journal of Investigative Dermatology.]

Previous research has clearly indicated that LED photodynamic therapy using wavelengths between the yellow and infrared range significantly increases collagen production in photoaged skin.


Now there’s evidence that it also slows collagen destruction.

Evidence of LED Therapy Collagen Increase


In Vivo
Studies using full- or split-face treatments with yellow (590 nm), red (630, 633 nm), or red in combination with infrared (830 nm) light produced significant increases in collagen production.

• Weiss et al. (2005) – eight LED 590 nm treatments over 4 weeks produced a 28% (range of 10–70%) average increase in density.

• Lee et al. (2007) – two times a week for four weeks, three randomly selected groups were treated with LEDs at

o 633  nm,
o 830 nm, or
o a combination of 633 and 830 nm.

All the treatment groups experienced a significant increase in the amount of collagen, while a fourth control group did not.

In Vitro
Significant collagen increase after LED treatment has been documented in:

• Fibroblast cultures (McDaniel et al., 2002; Huang et al., 2007);
• Third-degree burn wound-healing models (Meireles et al., 2008a, 2008b); and
• Human blister fluids (Barolet et al., 2005).


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Come back tomorrow to learn how LED Photodynamic Therapy May Also Slow Collagen Destruction.

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