Teprenone, Telomeres and More

[This report started yesterday.]

The various sites which feature Teprenone-based products give the same explanation you have heard – almost to the letter. They refer to studies but don’t share them. So I did a patent search for topical Teprenone.

[The drug Teprenone (geranylgeranylacetone) in capsule form is used to treat gastric ulcers in some parts of the world under the brand name Selbex. It is manufactured by Eisai (Japan). It protects the mucosal lining of the stomach and speeds healing of pre-existing lesions. Teprenone is also used in the treatment of glaucoma, hepatitis C, skin cancer and diseases involving keratinization (e.g. icthyosis and keratosis pilaris)]

The in vivo test results for topical Teprenone presented in the patent filing are equally impressive as its drug uses. However, the study presented was single-blind and involved only 24 women. Again on the plus side, objective measures were used to quantify results. No phrases like, “60% of subjects perceived smoother skin and a reduction of wrinkles.”

The U.S. patent for topical Teprenone was granted in 1995 and filed internationally with the World Intellectual Property Organization in 2006. The details which follow are from the filing by Sederma (France) and Karl Lintner (US), co-inventor with Claire Mas-Chamberlain.

Patent Filing Claims for Topical Teprenone
“Summary of the Invention: We have … discovered the interesting properties of … Teprenone to fight against the multifactorial signs of aging … The cutaneous functional and structural improvements observed and measured are: improved hydratation, decreased transepidermal water loss, reduction of UV spots; and improved firmness and tone, smoother skin, tighter pores and decreased redness.”

It appears that topical Teprenone does far more than protect the telomeres.

The study results on topical Teprenone tomorrow.

Tags: teprenone, topical teprenone, skin anti-aging, effective anti-aging ingredients, patent for topical teprenone, topical teprenone study results, anti-aging skin care, teprenone skincare products